Backup (and other operations) to HPE LTO tape drives may constantly fail after installation of Veeam Backup & Replication 9.5 Update 4b (18.104.22.16866).
Veeam fails to connect to the tape drive and returns the following errors:
[18.07.2019 15:49:24] <01> Warning TapeDrive alert: The tape drive has a problem with the application client interface
[18.07.2019 15:49:58] <01> Error Tape error: '1117' (The request could not be performed because of an I/O device error) (Veeam.Backup.Common.CCppComponentException)
[18.07.2019 15:49:58] <01> Error in c++: TapeHandle failed to get tape drive parameters.
[18.07.2019 15:49:58] <01> Error in c++: Tape initialization FAILED.
However, the tape drive is recognized correctly in the device manager and no hardware related errors are reported in the Windows System log.