When you back up/replicate/copy/clone a Windows 2008 R2 virtual machine with the VMXNET3 network adapter, the resulting virtual machine obtains a new NIC, and all network settings have to be adjusted manually.
The original VM:
When pinging the VM, a SureBackup job fails with the Destination host unreachable error, which can be seen in the SureBackup job log:
[timestamp] <01> Error [SureBackup] [Name] [PingTest] End 'Network adapter 1: IP address 'xxx.xx.xx.xxx', failed - destination host unreachable'
To resolve the issue for Windows 2008 R2 or Windows 7 versions prior to Service Pack 1, install the hotfix described in the Microsoft Knowledge Base article №2344941.
To resolve the issue for Windows 2008 R2 or Windows 7 versions post Service Pack 1,install the hotfix described in the Microsoft Knowledge Base article №2550978.
As a workaround, you can reconfigure the original machine to use the E1000 or other PCI network interface.