Veeam Agent for Microsoft Windows and Veeam Agent for Linux can be deployed using agent management via protection groups in Veeam Backup & Replication. This configuration will require network connectivity between the Veeam Backup Server and machines where agents are deployed.
You can deploy the Veeam Backup Server for agent management either in Azure from the Azure Marketplace or, if necessary, in Azure Public MEC. Ensure the appropriate networking is in place. For example, if deploying in Azure, you can peer a vNet in Azure with one in Azure Public MEC.
Should you want to deploy on-premises, you can use standard Azure networking concepts, such as a private link between this and your Azure Public MEC deployment.