Veeam Backup & Replication Communication With Azure Proxy Fails With "The RPC server is unavailable"

In addition to checking local routers and firewalls to ensure outbound traffic to the Azure Proxy VM over port 443^[1] is allowed, review the following Azure side configuration:

Check if the Azure Subnet that the Azure Proxy is using is associated with an Azure Firewall or a Network Security Group (NSG).

For subnet associated with NSG

Review the existing NSG rules, and if not configured, allow connections from the Veeam Backup server over port 443^[1].

Alternatively, an NSG rule can be created with the highest priority (100) to allow connections over 443^[1] using Azure CLI, PowerShell, or the Web Portal.

Reference: Azure Network Security Group

For subnet associated with Azure Firewall

By default, the Azure Firewall denies all traffic. Review the Azure Firewall configuration and ensure that a rule collection is configured to allow the traffic over port 443^[1]. If it is a restore of Linux based computer, also allow port 22.

Reference: Azure Firewall Rules